研究成果


第 1 到 29 筆結果，共 29 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Enhancing the identification of voriconazole-associated hepatotoxicity by targeted metabolomicsChiang, Yi-Hsuan; Cheng, Chih-Ning; Chuang, Pei-Jiun; YEE-CHUN CHEN ; Chen, Yi-Jing; CHING-HUA KUO ; SHU-WEN LIN ; LIN-CHAU CHANG International journal of antimicrobial agents00
22023Regulatory considerations for generic products of non-biological complex drugsLiu, Yu-Hsuan; Chen, Yi-Shuo; Tseng, Ting; Jiang, Min-Lin; Gau, Churn-Shiouh; LIN-CHAU CHANG Journal of food and drug analysis11
32022Orphan drug development: The impact of regulatory and reimbursement frameworksHuang, Yu-Jun; Chao, Wan-Yu; CHI-CHUAN WANG ; LIN-CHAU CHANG Drug discovery today11
42022Corrigendum to “The impact of the rare disease and Orphan Drug Act in Taiwan” [J Food Drug Anal 29 (2021) 717e725]Hsiang, Ning Chun; Huang, Weng Foung; Gau, Churn Shiouh; Tsai, Teng Wen; LIN-CHAU CHANG Journal of Food and Drug Analysis00
52021The impact of the rare disease and Orphan Drug Act in TaiwanHsiang, Ning-Chun; Huang, Weng-Foung; Gau, Churn-Shiouh; Tsai, Teng-Wen; LIN-CHAU CHANG Journal of food and drug analysis12
62021Investigation of Factors Associated With Immunogenicity Labeling Updates and Characteristics of Biologics License ApplicationsJiang, Ai-Lei; Breder, Christopher D; LIN-CHAU CHANG Clinical pharmacology and therapeutics11
72021Cell metabolomics analyses revealed a role of altered fatty acid oxidation in neurotoxicity pattern difference between nab-paclitaxel and solvent-based paclitaxelHuang J.-W.; CHING-HUA KUO ; Kuo H.-C.; JIN-YUAN SHIH ; Tsai T.-W.; LIN-CHAU CHANG PLoS ONE64
82021Differences in Fatty Acid Oxidation between Nab-Paclitaxel- And Solvent-Based Paclitaxel-Treated A549 Cells Based on MetabolomicsHuang J.-W.; CHING-HUA KUO ; Kuo H.-C.; JIN-YUAN SHIH ; Tsai T.-W.; LIN-CHAU CHANG ACS Omega22
92019Improved Dried Blood Spot-Based Metabolomics Analysis by a Postcolumn Infused-Internal Standard Assisted Liquid Chromatography-Electrospray Ionization Mass Spectrometry MethodChepyala, Divyabharathi; Kuo, Han Chun; KANG-YI SU ; Liao, Hsiao Wei; Wang, San Yuan; Chepyala, Surendhar Reddy; LIN-CHAU CHANG ; CHING-HUA KUO Analytical Chemistry1410
102019Evaluation and Optimization of Sample Handling Methods for Quantification of Short-Chain Fatty Acids in Human Fecal Samples by GC-MSHsu, Ya-Lin; CHIEH-CHANG CHEN ; Lin, Ya-Ting; WEI-KAI WU ; LIN-CHAU CHANG ; Lai, Chang-Hao; MING-SHIANG WU ; CHING-HUA KUO Journal of proteome research4547
112019Investigation of quality review issues and the association with application characteristics for new drug applications in first-cycle reviewsLiou J.-S.; LIN-CHAU CHANG Regulatory Toxicology and Pharmacology00
122019The biosimilar pathway in the USA: An analysis of the innovator company and biosimilar company perspectives and beyondLIN-CHAU CHANG Journal of Food and Drug Analysis54
132019Correlates of time to approval and other clinical development periodsBreder C.D.; VanHeusen M.; LIN-CHAU CHANG Drug Discovery Today00
142019Identification of factors associated with first-cycle drug approval rates and regulatory outcomes for new drug applicationsLIN-CHAU CHANG ; Vanheusen M.; Fang X.; Breder C.D.Pharmacological Research33
152018Recent updates and challenges on the regulation of precision medicine: The United States in perspectiveLIN-CHAU CHANG ; Colonna T.E.Regulatory Toxicology and Pharmacology10
162018Prognostic factors in epithelial ovarian cancer: A population-based studyLIN-CHAU CHANG ; CHIH-FEN HUANG ; Lai M.-S.; LI-JIUAN SHEN ; FE-LIN LIN WU ; WEN-FANG CHENG PLoS ONE6456
172018Thyrotropin receptor antibodies and a genetic hint in antithyroid drug-induced adverse drug reactionsLIN-CHAU CHANG ; Chang C.-C.; PEI-LUNG CHEN ; Wang S.-H.; Chen Y.-H.; Tsai Y.-H.; SHYANG-RONG SHIH ; WEI-YIH CHIU ; Fann C.S.-J.; WEI-SHIUNG YANG ; TIEN-CHUN CHANG Expert Opinion on Drug Safety55
182017Patterns of use and impact of standardised MedDRA query analyses on the safety evaluation and review of new drug and biologics license applicationsLIN-CHAU CHANG ; Mahmood R.; Qureshi S.; Breder C.D.PLoS ONE1110
192016Development of the risk-based, phased-in approach for the international harmonization of the regulation of container closure systems for drugs in TaiwanLIN-CHAU CHANG ; Kang J.-J.; Gau C.-S.Regulatory Toxicology and Pharmacology32
202015The evolution and challenges for the international harmonization of the regulation of pharmaceutical excipients in TaiwanLIN-CHAU CHANG ; Kang J.-J.; Gau C.-S.Regulatory Toxicology and Pharmacology32
212013Statistics, Quality Review Issues, and Beyond for Generic Drug Applications in TaiwanLIN-CHAU CHANG ; Gau C.-S.Therapeutic Innovation and Regulatory Science55
222009The clinical implications of blood adiponectin in cardiometabolic disordersLIN-CHAU CHANG ; KUO-CHIN HUANG ; YEN-WEN WU ; HSIEN-LI KAO ; CHI-LING CHEN ; LING-PING LAI ; HWANG, JUEY-JEN ; WEI-SHIUNG YANG Journal of the Formosan Medical Association5449
232008Determining Estrogens Using Surface-Assisted Laser Desorption/Ionization Mass Spectrometry with Silver Nanoparticles as the MatrixChiu, Tai-Chia; LIN-CHAU CHANG ; Chiang, Cheng-Kang; HUAN-TSUNG CHANG Journal of the American Society for Mass Spectrometry8679
242008Simultaneous separation of four types of steroid hormones by micellar electrokinetic chromatography with cetyltrimethylammonium bromideLIN-CHAU CHANG ; Chiu T.-C.; SHOEI-SHENG LEE ; CHING-HUA KUO ; TIEN-CHUN CHANG Journal of the Chinese Chemical Society33
252008Interfacial properties of Pluronics and the interactions between Pluronics and cholesterol/DPPC mixed monolayersLIN-CHAU CHANG ; Chang Y.-Y.; Gau C.-S.Journal of Colloid and Interface Science3938
262008Adiponectin: A biomarker of obesity-induced insulin resistance in adipose tissue and beyondJIN-YING LU ; KUO-CHIN HUANG ; LIN-CHAU CHANG ; Huang Y.-S.; Chi Y.-C.; Su T.-C.; CHI-LING CHEN ; WEI-SHIUNG YANG Journal of Biomedical Science8887
272006Cyclodextrin-modified microemulsion electrokinetic chromatography for separation of α-, γ-, δ-tocopherol and α-tocopherol acetateChang, Lin-Chau ; Chang, Huan-Tsung ; Sun, Shao-WenJournal of Chromatography A2825
282006Micellar electrokinetic chromatography for separation of a mixture of coptis alkaloids, scute flavonoids, and rhubarb anthraquinones and bianthronesLIN-CHAU CHANG ; Sun S.-W.Journal of Pharmaceutical and Biomedical Analysis3632
292005Interactions of Pluronics with phospholipid monolayers at the air-water interfaceLIN-CHAU CHANG ; Lin C.-Y.; Kuo M.-W.; Gau C.-S.Journal of Colloid and Interface Science4445