Project title
以X-射線結晶學探討人類第二型拓撲異構酵素TOP2alpha與TOP2beta之結構及其與抗癌藥物和DNA之交互作用
Internal ID
NSC99-2113-M002-008-MY3
Principal Investigator
Start Date
August 1, 2012
End Date
July 12, 2013
Partner Organizations
X-Ray Crystallographic Analyses of Human Type II Topoisomerases Top2alpha and Top2beta and Their Complexes with DNA and Antitumor Agents
Keywords
蛋白質結晶學
抗癌藥物
第二型拓撲異構酵素
蛋白-DNA交互作用
蛋白-藥物交互作用
protein crystallography
anticancer drug
type II topoisomerase
protein-DNA interaction
protein-drug interaction