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.National Taiwan University / 國立臺灣大學
Project / 研究計畫
Correlation between Various Urinary Exosomal Protein Biomarkers and Pathological Manifestation in Thyroid Follicular Neoplasm: Early and Pre-Operative Diagnosis of Follicular Thyroid Cancer = 尿外泌體蛋白質生物指標與甲狀腺濾泡腫瘤病理表現的相關性:濾泡性甲狀腺癌的早期和術前診斷
Correlation between Various Urinary Exosomal Protein Biomarkers and Pathological Manifestation in Thyroid Follicular Neoplasm: Early and Pre-Operative Diagnosis of Follicular Thyroid Cancer = 尿外泌體蛋白質生物指標與甲狀腺濾泡腫瘤病理表現的相關性:濾泡性甲狀腺癌的早期和術前診斷
Details
Primary Data
Project title
尿外泌體蛋白質生物指標與甲狀腺濾泡腫瘤病理表現的相關性:濾泡性甲狀腺癌的早期和術前診斷
Internal ID
NSTC111-2314-B002-227-MY3
Principal Investigator
CHIH-YUAN WANG
Start Date
August 1, 2024
End Date
July 31, 2025
Investigators
KUEN-YUAN CHEN
WAN-CHEN WU
SHYANG-RONG SHIH
Organizations
Internal Medicine
Partner Organizations
National Science and Technology Council
Description
Keywords
Exosome
Thyroglobulin
Thyroid follicular cancer
Pathology
Urine
Biological marker
Description
甲狀腺濾泡癌的術前診斷,迄今仍為內分泌學研究中,尚未解決的議題,因為目前只有病理學的術後解讀,才能成立甲狀腺濾泡癌之診斷,而且良性的甲狀腺濾泡腺瘤,在經過病理學之確認後,約有5至10%之病患,在若干年後,因肺部或骨頭轉移,才發現正確之診斷為甲狀腺濾泡癌。因此,本研究係基於本團隊在過去十年中,依動物模型及人體試驗建立之生物指標參數,部分已獲得我國及日本之專利,進行病理學之比對,希冀建立更完整之甲狀腺濾泡癌術前診斷生物指標,並且能成為真正臨床實用之診斷標的。
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