Project title
慢性Ｂ型肝炎與肝癌之新穎免疫治療-研究腸道菌叢與B型肝炎病毒共同演化以利用T細胞免疫反應治療B型肝炎(4/5)
Internal ID
MOST112-2326-B002-001
Principal Investigator
Start Date
August 1, 2023
End Date
July 31, 2024
Investigators
Organizations
Partner Organizations
Investigating Co-Evolution of Gut Microbiome and Hbv to Shape Host T Cell Responses for Hepatitis B and Immunotherapy (IV)
Keywords
chronic hepatitis B
T cell immunity
Gut microbiota
immunopeptidomics
T cell receptor
Description
本研究將利用人體臨床研究、小鼠模式、體外細胞模式，從各個角度探討腸道菌叢與辨識B型肝炎病毒之記憶T細胞如何控制病毒感染，有助於將來發展理想的慢性B型肝炎治療策略。