Project title
第二型運動失調症引發人類P/Q型鈣離子(Cav2.1)通道蛋白質降解現象之分子生理機制
Internal ID
MOST105-2320-B002-054-MY3
Principal Investigator
Start Date
August 1, 2016
End Date
July 12, 2017
Partner Organizations
The Molecular Physiological Mechanism Underlying Episodic Ataxia Type 2-Associated Protein Degradation of Human P/Q-Type Ca2+ (Cav2.1) Channels
Keywords
鈣離子通道 運動失調症 顯性抑制作用 泛素蛋白酶體系統 E3泛素連接酶 E2泛素接合酶
Calcium channel
Episodic ataxia
Dominant-negative effect
Ubiquitin-proteasome system
E3 ubiquitin ligase
E2 ubiquitin-conjugate enzyme