Project title
以小鼠與果蠅為模式探討臺灣本土遺傳性巴金森氏症的新穎致病基因突變UQCRC1之致病機轉與治療策略
Internal ID
MOST106-2314-B002-072-MY3
Principal Investigator
Start Date
August 1, 2017
End Date
July 31, 2018
Organizations
Partner Organizations
Exploration of the Pathogenic Mechanisms and Treatment Strategy of Novel Familial Parkinson’S Disease Causative Gene, Uqcrc1, in Mouse and Fly Models
Keywords
巴金森氏症
粒線體
電子傳遞鍊
動物模式
基因編輯
機轉治療
Parkinson’s disease
mitochondria
UQCRC1
ubiquinol-cytochrome c reductase core protein I
gene editing