Project title
探討第二型拓撲酶主導之DNA閘門的形成及其運作機制：基於結構生物學、生物化學、與理論計算的整合性分析
Internal ID
MOST106-2113-M002-021-MY3
Principal Investigator
Start Date
August 1, 2019
End Date
July 31, 2020
Partner Organizations
An Integrated Structural, Biochemical, and Computational Dissection of the Assembly and Operation of the Type II Topoisomerase-Mediated DNA Gate
Keywords
第二型DNA 拓撲異構酶
DNA 分子閘門
蛋白質與DNA 之交互作用
蛋白質-DNA 複合體之構形變化
生物巨分子X-射線晶體結構解析
type II DNA topoisomerase
enzyme-mediated DNA-gate
protein-DNA interactions
conformational change of protein-DNA complex
macromolecular X-ray crystallography