Inhibition of Neddylation to Conquer Tumor Progression and Drug Resistance in Urothelial Carcinoma---Searching for Novel Therapeutic Strategy

Project title

抑制接合作用(Neddylation)克服尿路上皮癌腫瘤進展及抗藥性---尋找新的治療模式

Internal ID

NSC102-2314-B002-123-MY2

Principal Investigator

Start Date

August 1, 2014

End Date

July 12, 2015

Partner Organizations

Project Web Site

Keywords

膀胱尿路上皮癌 (Bladder urothelial carcinoma)

抗藥性（Drug resistance）

泛素-蛋白酶系统(Ubiquitin-proteasome system)

Nedd8分子接合作用（neddylation）

腫瘤幹細胞 (cancer stem cell)

Bladder urothelial carcinoma

Drug resistance

Ubiquitin-proteosome
pathway

neddylation

NEDD8 cancer stem cell (CSCs)