Prenylbicyclogermacrane Diterpenoids from the Formosan Soft Coral Nephthea pacifica
Resource
Journal of Natural Products 68 (1): 74-77
Journal
Journal of Natural Products
Journal Volume
68
Journal Issue
1
Pages
74-77
Date Issued
2005
Date
2005
Author(s)
Abstract
Ten new prenylbicyclogermacrane diterpenoids, pacificins A-J (1-10), were isolated from the methylene chloride solubles of the Formosan soft coral Nephthea pacifica. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
Other Subjects
dichloromethane; diterpenoid; pacificin A; pacificin B; pacificin C; pacificin D; pacificin E; pacificin F; pacificin G; pacificin H; pacificin I; pacificin J; unclassified drug; animal cell; article; cancer cell; carbon nuclear magnetic resonance; controlled study; coral; cytotoxicity; drug isolation; drug structure; human; human cell; in vitro study; nonhuman; nuclear Overhauser effect; proton nuclear magnetic resonance; Animals; Anthozoa; Antineoplastic Agents; Diterpenes; Drug Screening Assays, Antitumor; Leukemia P388; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Taiwan; Alcyonacea; Animalia; Anthozoa
Type
journal article
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