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  4. Diagnosis of oral cancer by light-induced autofluorescence spectroscopy using double excitation wavelengths
 
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Diagnosis of oral cancer by light-induced autofluorescence spectroscopy using double excitation wavelengths

Journal
Oral Oncology
Journal Volume
35
Journal Issue
2
Pages
144-150
Date Issued
1999
Author(s)
Wang, Chih-Yu
Chiang, Huihua Kenny
CHIN-TIN CHEN  
CHUN-PIN CHIANG  
Kuo, Ying-Shiung
SONG-NAN CHOW  
DOI
10.1016/S1368-8375(98)00107-9
URI
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032991107&partnerID=MN8TOARS
http://scholars.lib.ntu.edu.tw/handle/123456789/346836
Abstract
A cancer diagnostic algorithm, light-induced autofluorescence spectroscopy using double excitation wavelengths, was employed for distinguishing between cancerous and normal oral mucosa. For emission spectra at the shorter excitation wavelengths (280, 290, and 300 nm), the ratio between the area under 325-335 nm and the area under 465-475 nm was calculated. In the same way, for emission spectra at the longer excitation wavelengths (320, 330, and 340 nm), the ratio between the area under 375-385 nm and the area under 465-475 nm was calculated. Receiver operating characteristic curves were used to evaluate the performance of algorithms using single and the double (by combining shorter and longer) excitation wavelengths. The results showed that better performance, up to sensitivity 81.25%, specificity 93.75%, and positive predictive value 92.86%, could be achieved by using the double excitation wavelengths. The present study can be useful as a basis for further investigation on in vivo autofluorescence measurement and analysis using double excitation wavelength.
Subjects
Autofluorescence spectroscopy; Double excitation wavelengths; Oral cancer
SDGs

[SDGs]SDG3

Other Subjects
algorithm; article; autofluorescence; clinical article; controlled study; diagnostic accuracy; diagnostic value; human; human cell; human tissue; mouth cancer; photosynthetic phosphorylation; prediction; priority journal; receiver operating characteristic; spectral sensitivity
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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