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  4. Feasibility and safety of nonintubated thoracoscopic lobectomy for geriatric lung cancer patients
 
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Feasibility and safety of nonintubated thoracoscopic lobectomy for geriatric lung cancer patients

Journal
Annals of Thoracic Surgery
Journal Volume
95
Journal Issue
2
Pages
405-411
Date Issued
2013
Author(s)
CHUN-YU WU  
JIN-SHING CHEN  
Lin Y.-S.
TUNG-MING TSAI  
MING-HUI HUNG  
KUANG-CHENG CHAN  
YA-JUNG CHENG  
DOI
10.1016/j.athoracsur.2012.10.082
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84872770560&doi=10.1016%2fj.athoracsur.2012.10.082&partnerID=40&md5=1ee98c66ed99f6b6523b18804eff71bb
https://scholars.lib.ntu.edu.tw/handle/123456789/579725
Abstract
Background: The feasibility and safety of thoracoscopic lobectomy using anesthesia without tracheal intubation for treatment of geriatric non-small cell lung cancer patients is unclear, although it has been used with success in younger populations. Methods: From 2009 through 2011, 84 consecutive patients aged 65 years or older with stage I or II non-small cell lung cancer underwent thoracoscopic lobectomy. Among them, 36 patients were treated without tracheal intubation using epidural anesthesia, intrathoracic vagal blockade, and sedation (nonintubated group). The other 48 patients were treated with single-lung ventilation under general anesthesia intubated with a double-lumen tube (intubated group). The perioperative profiles and short-term outcomes of the two groups were compared. Results: The 84 patients were a mean age of 73.0 years (range, 65-87 years). Both groups had comparable preoperative demographic and cancer staging profiles. The anesthetic duration of the nonintubated group was shorter. Both groups had comparable operation duration and blood loss. One patient in the nonintubated group was converted to tracheal intubation due to persistent hypoxemia. Postoperatively, the two groups had comparable hospital stays, complication rates, and dissected lymph nodes. Stridor was noted in 3 patients and delirium in 4 in the intubated group, but none occurred in the nonintubated group. Conclusions: Nonintubated thoracoscopic lobectomy is technically feasible and was as safe as thoracoscopic lobectomy performed with tracheal intubation in the geriatric lung cancer patients. Thoracoscopic lobectomy without tracheal intubation during anesthesia is a valid alternative for managing selected geriatric patients with non-small cell lung cancer. ? 2013 The Society of Thoracic Surgeons.
SDGs

[SDGs]SDG3

Other Subjects
aged; article; cancer patient; cancer staging; endotracheal intubation; epidural anesthesia; feasibility study; female; geriatric patient; hospitalization; human; hypoxemia; lobectomy; lung non small cell cancer; lung ventilation; lymph node dissection; major clinical study; male; operation duration; postoperative hemorrhage; preoperative period; priority journal; prospective study; sedation; stridor; thoracoscopy; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Pneumonectomy; Prospective Studies; Thoracoscopy
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

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