Susceptibility contrast perfusion MRI for the investigation of ischemic stroke (2/2)
Date Issued
2001-07-31
Date
2001-07-31
Author(s)
DOI
892213E002193
Abstract
The purpose of this two-year project is
to develop a series of image analysis methods
on clinical perfusion-weighted magnetic
resonance imaging (MRI) using the concept
of dynamic susceptibility contrast. The
specific target of the project is cerebral
ischemia. In the first fiscal year we have
implemented and optimized conventional
analysis methods to estimate the relative
parameters. The analysis software has also
been successfully transformed into clinical
MR system platform. In the second fiscal
year, the pitfalls inherent in the absolute
quantification of perfusion parameters
commonly used as the international standard
have been analyzed in detail and a proposed
remedy: maximum signal drop (MSD) tested
on stroke patients and shown high
dependence on CBF. In this report, the
estimation errors on the absolute perfusion
parameters with the conventional procedure
are analyzed and the clinical feasibility of the
proposed novel algorithm are shown.
Subjects
perfusion
magnetic resonance
cerebral ischemia
maximum signal
drop
drop
absolute quantification of
perfusion parameter
perfusion parameter
Publisher
臺北市：國立臺灣大學電機工程學系暨研究所
Type
report
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