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Integrated, cascading enzyme-/chemocatalytic cellulose conversion using catalysts based on mesoporous silica nanoparticles
Journal
ChemSusChem
Journal Volume
7
Journal Issue
12
Pages
3241-3246
Date Issued
2014
Author(s)
Abstract
This article reports a novel approach to deconstructing cellulose into 5-hydroxymethylfurfural (HMF) with a high yield (46.1%) by integrating a sequential enzyme cascade technique in an aqueous system with solid acid catalysis in an organic-solvent system. We executed the rational design and synthesis of mesoporous silica nanoparticles (MSNs) with various pore sizes and surface functionalities, which proved to be useful for the immobilization of various enzymes (i.e., cellulase and isomerase) and nanoparticles (i.e., magnetic Fe3O4) and for functionalization of various acid groups (i.e., H2PO3, COOH, and SO3H). We separately applied the synthesized biocatalysts (i.e., cellulase-Fe3O4@MSN and isomerase-Fe3O4@MSN) and chemical catalysts (i.e., HSO3-MSN) in a sequential cellulose-to-glucose, glucose-to-fructose, and fructose-to-HMF conversion, respectively, across both aqueous- and organic-solvent systems after the optimization of reaction conditions (e.g., reaction temperature, water ratio, catalyst amount). The integrated enzymatic and chemocatalytic concept in this study could be an effective and economically friendly process for various catalytic applications. © 2014 Wiley-VCH Verlag GmbH & Co. KGaA.
Subjects
Biomass; Enzyme catalysis; Immobilization; Mesoporous materials; Renewable resources
SDGs
Other Subjects
Biocatalysts; Biomass; Catalysis; Cellulose; Enzyme immobilization; Fructose; Glucose; Nanomagnetics; Nanoparticles; Organic solvents; Pore size; Radioactive waste vitrification; Silica; Synthesis (chemical); 5 hydroxymethyl furfurals; Catalytic applications; Enzyme catalysis; Mesoporous silica nanoparticles; Reaction temperature; Renewable resource; Solid acid catalysis; Surface functionalities; Mesoporous materials; cellulose; nanoparticle; silicon dioxide; catalysis; chemistry; Catalysis; Cellulose; Nanoparticles; Silicon Dioxide
Type
journal article