Preparation of Benzo[a]fluorenes via Pd-Catalyzed Annulation of 5-(2-Bromophenyl)pent-3-en-1-ynes
Journal
The Journal of Organic Chemistry
ISSN
0022-3263
1520-6904
Date Issued
2024-08-09
Author(s)
Abstract
A palladium-promoted cascade cyclization of 5-(2-bromophenyl)pent-3-en-1-ynes is developed for the synthesis of benzo[a]fluorene derivatives. The reaction proceeds with oxidative addition of C-Br, insertion, C-H activation, and reductive elimination in sequential steps.
Publisher
American Chemical Society (ACS)
Type
journal article