Impact of oral hygiene on head and neck cancer risk in a Chinese population
Journal
Head and Neck
Journal Volume
39
Journal Issue
12
Pages
2549-2557
Date Issued
2017
Author(s)
Kawakita D
Lee Y.-C.A
Li Q
Chen Y
Chen C.-J
Hsu W.-L
Zhu C
Pan J
Shen H
Ma H
Cai L
He B
Wang Y
Zhou X
Ji Q
Zhou B
Wu W
Ma J
Boffetta P
Zhang Z.-F
Dai M
Hashibe M.
Abstract
Background: Although the impact of oral hygiene on head and neck cancer risk has been investigated, few studies have been conducted among the Asian population. Methods: We conducted a multicenter case-control study to investigate this potential association. We performed unconditional multiple logistic regression models adjusted by potential confounders. Results: We observed an inverse association of frequency of dental visits with head and neck cancer risk, with an adjusted odds ratio (OR) of 3.70 (95% CI 2.51-5.45) for never dental visits compared with ?1 time/year (Ptrend <.001). We also observed a positive association between the number of missing teeth and head and neck cancer risk, with an adjusted OR for ?5 missing teeth compared with <5 missing teeth of 1.49 (95% CI 1.08-2.04). Combining multiple oral hygiene indicators, poor oral hygiene scores increased head and neck cancer risk. Conclusion: Poor oral hygiene may increase head and neck cancer risk in the Chinese population. Therefore, improving oral hygiene may contribute to reducing the head and neck cancer risk in the Chinese population. ? 2017 Wiley Periodicals, Inc.
Subjects
Chinese; dental care; head and neck cancer; oral hygiene; risk
SDGs
Other Subjects
adult; aged; Article; betel quid; cancer patient; cancer risk; case control study; Chinese; comparative study; controlled study; dental prophylaxis; drinking behavior; female; head and neck cancer; human; ICD-O-3; major clinical study; male; mastication; medical history; mouth hygiene; multicenter study; priority journal; smoking; Taiwanese; tooth; age distribution; cancer staging; China; clinical trial; confidence interval; head and neck tumor; incidence; middle aged; mouth hygiene; multivariate analysis; odds ratio; pathology; risk assessment; sex ratio; squamous cell carcinoma; statistical model; tumor invasion; very elderly; young adult; Adult; Age Distribution; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Case-Control Studies; China; Confidence Intervals; Female; Head and Neck Neoplasms; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Staging; Odds Ratio; Oral Hygiene; Risk Assessment; Sex Distribution; Young Adult
Publisher
John Wiley and Sons Inc.
Type
journal article