Verbatim and Gist Memory in Chronic Schizophrenia
Date Issued
2007
Date
2007
Author(s)
Wu, Yue-Mei
DOI
zh-TW
Abstract
Normal memory depends upon both adequate verbatim and gist memory functioning. The issue regarding whether defective memory function in schizophrenic patients results from either impaired verbatim, gist memory functioning, or poor false alarm monitoring has been distinctly investigated. However, little has approached the effects of verbatim memory, gist memory, or false alarm concurrently on these patients’ poor memory functioning. Using the Deese-Roediger-McDermott (DRM) paradigm task, the present study was to make an attempt to explore their constructive processes of memory. Four specific objectives of this study were as follows: to (1) explore neurocognitive functions in patients with chronic schizophrenia, (2) approach the patient’s verbatim memory, gist memory, and unrelated false alarm through the DRM paradigm task, (3) investigate the possible underlying neuropsychological mechanisms regarding the verbatim memory, gist memory, and unrelated false alarm, and (4) examine the appropriateness of the DRM paradigm task to be a clinical tool in assessing gist memory. Forty patients with chronic schizophrenia and 30 healthy normal controls, matched for the sex, age, and education level, participated in the study. All subjects were given a battery of neuropsychological tests and the DRM paradigm task. The results revealed that patients evidenced significant deficits of intellection, attention, episodic memory, language and semantic memory, and executive function. On the DRM paradigm task, the mean gist memory score of the patients was significantly lower than that of normal controls while mean verbatim memory and unrelated false alarm scores of the patients were compatible with those of normal controls. For normal controls and patients, their gist memory scores were significantly positively correlated with the Vocabulary subtest scores. However, only the patients’ gist memory scores were also associated with their working memory index and Visual Reproduction subtest scores. Moreover, the patients had significantly lower gist memory scores of the DRM paradigm task and thematic scores of the Logical Memory subtest compared with their normal counterparts. Based on the results, it thus appears that the patients’ defective gist memory might be related to dysfunction of the frontal-temporal loop, and is further suggested that the DRM paradigm task might be an alternative clinical measure to assess gist memory if its limitations are taken into account.
Subjects
精神分裂症
逐項記憶
要旨記憶
假警報。
schizophrenia
verbatim memory
gist memory
false alarm
Type
other
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