CYBA as a Potential Biomarker for Renal Cell Carcinoma: Evidence from an Integrated Genetic Analysis
Journal
Cancer genomics & proteomics
Journal Volume
20
Journal Issue
5
Date Issued
2023
Author(s)
Chang, Chi-Fen
Huang, Shu-Pin
Hsueh, Yu-Mei
Chen, Pei-Ling
Lee, Cheng-Hsueh
Geng, Jiun-Hung
Bao, Bo-Ying
Abstract
Oxidative stress plays an important role in various pathogenic processes, and disruption in the coordinated production of NADPH oxidase (NOX)-derived reactive oxygen species has been associated with carcinogenesis. However, little is known about whether genetic variants in NOX can contribute to the development of renal cell carcinoma (RCC).
Subjects
NADPH oxidase; Renal cell carcinoma; differentially expressed gene; prognosis; single-nucleotide polymorphism
Type
journal article