Differential expression of osteoblast-specific factor 2 and polymeric immunoglobulin receptor genes in nasopharyngeal carcinoma
Journal
Head and Neck
Journal Volume
27
Journal Issue
10
Pages
873-882
Date Issued
2005
Author(s)
Chang Y.
Lee T.-C.
Li J.-C.
Lai T.-L.
Chua H.-H.
Chen C.-L.
Chou C.-K.
Sheen T.-S.
Abstract
NPC shows significant upregulation of OSF-2 and downregulation of pIgR. Expression of OSF-2 is likely to play a role in the pathogenesis of NPC. In addition, expression of OSF-2 and pIgR is disassociated with the expression of their regulatory cytokines in NPC biopsy specimens, suggesting that the tumors may have altered responses to certain cytokines.
SDGs
Type
journal article