SnapShot: RNA Structure Probing Technologies
Journal
Cell
Journal Volume
175
Journal Issue
2
Pages
600-6000
Date Issued
2018
Author(s)
Abstract
Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules. Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules. © 2018 Elsevier Inc.
Other Subjects
cell function; DNA probe; high throughput sequencing; in vitro study; in vivo study; RNA structure; short survey; animal; biology; conformation; human; procedures; sequence analysis; software; ultrastructure; RNA; Animals; Computational Biology; High-Throughput Nucleotide Sequencing; Humans; Nucleic Acid Conformation; RNA; Sequence Analysis, RNA; Software
Type
short survey