In-vivo Millimeter Wave Measurement of Mouse Tissue Absorption
Date Issued
2009
Date
2009
Author(s)
Kuo, Chiu-Chung
Abstract
THz radiations, or simply THz, are electromagnetic waves lying on the spectrum between microwaves and infrared radiations. Due to distinguishable absorption spectra in this band and other advantages, THz is a potential field for biomedicine inspections. One of the most important THz applications is malignant tumor detection. Currently however, there is no in-vivo transmission detection due to critical liquid water absorption. Since liquid water absorption with decreased frequency is weaker, this work selects the lowest frequency in the THz band, the millimeter wave, for transmission measurement of in-vivo tissues. The current study sets up a simple room temperature transmission power measurement system with SNR (signal to noise ratio) of about 60 dB at 108 to 143 GHz. The nude mice implanted with breast cancer and fat are chosen as the animal models. Results of this study show that the attenuation coefficients of skin and tumors are indistinguishable, a little less than that of liquid water, and obviously larger than that of fat. To conclude, THz detection capability in low frequency is not to discriminate materials, but to measure water content.
Subjects
In-vivo transmission measurement
attenuation coefficients
breast cancer
fat
millimeter wave
THz
SDGs
Type
thesis
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