Optical Enhanced Nanoparticle-Based Surface Plasmon Resonance Sensor
Date Issued
2004
Date
2004
Author(s)
Lo, Ya-Ling
DOI
en-US
Abstract
Nanotechnology is the most attractive term in science literature. And the noble metal nanoparticles which has size- and shape-dependent properties has promoted a great deal of excitement during the last decades. These nanostructure materials have potential in many areas such as biological detection, drug delivery system, low threshold lasers, sensors and optical filters.
In this thesis, we utilize the Kretschmann configuration surface plasmon resonance to investigate the optical properties of two types of nanoparticles, the rod- and sphere-shaped nanoparticles with four different sizes of nanosphere and four different absorption wavelengths of nanorods. The nanoparticles are deposited on the gold substrate with self-assembly technique. The ellipsometry method is utilized for the measurements of the optical constants of the nanosphere layer. Furthermore, the nanorods are employed for the testing of bio-sensitivity with ALV virus and IgG antibody.
The nanosphere layer exhibits the size-dependent FWHM and reflectance of the surface plasmon resonance dip. The nanorods display a narrower SPR dip than the nanosphere. These are partly related to the nanoparticle behaviors of scattering spectra. The depositions of nanoparticle enhance the optical field in the vicinity of the particle and form a strong perturbation of the electromagnetic filed. Thus this phenomenon greatly influences the variation of the refractive index. We utilize the mechanism to amplify the SPR signal and can detect the concentration of antigen down to 6x10^-13 g/mL so far.
Subjects
金奈米粒子
表面電漿共振
surface plasmon resonance
gold nanoparticle
nanoro
Type
thesis
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