Peripheral Neuropathy and Quality of Sleep in Patients Receiving Dialysis
Date Issued
2008
Date
2008
Author(s)
Chen, Wei-Chun
Abstract
Among dialysis patients, one of the most common neuropathy is peripheral neuropathy, charactered by symptoms of sensori-motor polyneuropathy. The purposes of this crossectional, correlational study were to identify (1) the symptoms and severity of peripheral neuropathy in dialysis patients, and (2) the correlation between peripheral neuropathy with or without peripheral neuropathic pain versus quality of sleep. Eligible patients (who receive dialysis therapy more than 3 months) were recruited from a medical center in Taipei. Data were collected by Michigan Neuropathy Screening Instrument (MNSI), Neuropathic Pain Scale (NPS), Medical Outcome Study Sleep Scale (MOS-Sleep Scale), Symptom Severity Scale (SSS), and Hospital Depression Subscale (HDS). A total of 162 dialysis patients were studied. The results indicated that 48 patients (30％) with a clinical MNSI score≧2 had peripheral neuropathy. The most common symptom was numbness (64.6％), followed by worse at night (41.7％) and prickling (37.5％). Of 48 patients, 19 had peripheral neuropathic pain, charactered by unpleasant feeling and sharp pain (73.7％). The scores of peripheral neuropathy were more severe in hemodialysis patients than in peritoneal dialysis patients (p=.03), especially under adequacy dialysis (Kt/V<1.2) with hemodialysis. Peripheral neuropathy was associated with age (p<.001), and potassium (p=.003), especially age over 65 or potassium over 4.3 mmole/L. There were also significant relationship between peripheral neuropathy and quality of sleep (p<.01); and between neuropathic pain and quality of sleep (p<.05). Patients (11.7％) with peripheral neuropathy and neuropathic pain experienced the worst quality of sleep. In conclusion, our data provides more information about peripheral neuropathy perceived by dialysis patients for further clinical care and related studies.
Subjects
ESRD
dialysis
peripheral neuropathy
neuropathic pain
quality of sleep
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