Prognosis of medication-related osteonecrosis of the jaws in cancer patients using antiresorptive agent zoledronic acid
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
120
Journal Issue
8
Date Issued
2021-08
Author(s)
Lee, Yen-Ching
Wang, Jai-Jen
Abstract
Anti-resorptive agents are commonly used in cancer patients with bone metastasis or multiple myeloma (MM). An adverse event termed medication-related osteonecrosis of the jaws (MRONJ) was discovered in patients using these agents but relatively little attention has been paid to its prognosis. Our aims were to find out the treatment outcomes and prognostic indicators of MRONJ in cancer patients who received zoledronic acid as antiresorptive therapy.
Subjects
Bone metastasis; Cancer; Medication-related osteonecrosis of the jaws (MRONJ); Prognosis; Zoledronic acid
SDGs
Other Subjects
amoxicillin; amoxicillin plus clavulanic acid; analgesic agent; biological marker; carboxy terminal telopeptide; chlorhexidine; clindamycin; collagen type 1; mouthwash; zoledronic acid; bisphosphonic acid derivative; bone density conservation agent; zoledronic acid; adult; aged; alcohol abstinence; anemia; Article; bone metastasis; bone resection; bone turnover; breast cancer; cancer patient; cancer staging; chronic disease; clinical evaluation; cohort analysis; cone beam computed tomography; conservative treatment; debridement; demography; diabetes mellitus; female; follow up; human; jaw osteonecrosis; major clinical study; male; mandible; maxilla; medication related osteonecrosis of the jaw; multiple myeloma; periimplantitis; periodontitis; prescription; prognosis; prostate cancer; questionnaire; radiodiagnosis; retrospective study; sequestrectomy; smoking cessation; surgery; tooth extraction; tooth implantation; treatment duration; treatment outcome; treatment response; bone necrosis; bone tumor; jaw; jaw osteonecrosis; prognosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Humans; Jaw; Male; Osteonecrosis; Prognosis; Retrospective Studies; Zoledronic Acid
Type
journal article