Proton-Echo-Planar-Spectroscopy-Imaging (PEPSI): Developments and Applications
Date Issued
2007
Date
2007
Author(s)
Tsai, Shang-Yueh
DOI
en-US
Abstract
Magnetic Resonance Spectroscopy (MRS) has been used for almost three decades to investigate the living tissue for prognostic or diagnostic markers. Fast magnetic resonance spectroscopy imaging technique, PEPSI, can reduce the long scan time of conventional SI to a single minute, which significantly raise the clinical potential of SI. In this thesis, a PEPSI sequence suitable for general clinical application has been implemented on the clinical machine at various field strengths. We investigate the possibility to combine PEPSI with parallel imaging techniques to further improve the temporal resolution of SI. The experiments showed that the parallel acceleration on PEPSI is feasible with the enrollment of multiple array coils to achieve sub-minute measurement. With the current developed large-N array coils, the temporal resolution of SI can be further reduce. Beneficial from the fast property of PEPSI technique, spatial distributed metabolite T2 relaxation time can be derived in clinical acceptable time. Consistent and reliable results were observed using the proposed protocol based on PEPSI sequence. The acquisition of less than 30 minutes is potentially applicable in clinical practice.
Subjects
磁核共振頻譜
面迴訊氫原子核頻譜影像
平行影像
自旋自旋遲緩時間
MRS
PEPSI
Parallel imaging
large-N array coils
T2 relaxation time.
Type
thesis
File(s)![Thumbnail Image]()
Loading...
Name
ntu-96-D92921031-1.pdf
Size
23.31 KB
Format
Adobe PDF
Checksum
(MD5):b6d49ba8a99be2a89fd8fca560e5edf9