Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis
Journal
The New England journal of medicine
Journal Volume
380
Journal Issue
10
Pages
981
Date Issued
2019-03-07
Author(s)
Choon S.-E.
Marrakchi S.
David Burden A.
Morita A.
Turki H.
Hall D.B.
Shear M.
Baum P.
Padula S.J.
Thoma C.
SDGs
Other Subjects
bi 655130; cytokine; cytokine receptor antagonist; interleukin 36; monoclonal antibody; unclassified drug; IL36RN protein, human; interleukin derivative; interleukin receptor; interleukin-36 receptor, human; drug efficacy; gene; gene mutation; generalized pustular psoriasis; generalized pustular psoriasis; human; IL36RN gene; Letter; priority journal; proof of concept; pustular psoriasis; antagonists and inhibitors; clinical trial; female; genetics; intravenous drug administration; male; metabolism; mutation; phase 1 clinical trial; psoriasis; severity of illness index; Administration, Intravenous; Female; Humans; Interleukins; Male; Mutation; Psoriasis; Receptors, Interleukin; Severity of Illness Index
Publisher
MASSACHUSETTS MEDICAL SOC
Type
journal article