Associations Between Particulate Sulfate and Organic Carbon Exposures and Heart Rate Variability in Patients With or at Risk for Cardiovascular Diseases
Resource
Journal of Occupational and Environmental Medicine v.49 n.6 pp.610-617
Journal
Journal of Occupational and Environmental Medicine
Journal Volume
v.49
Journal Issue
n.6
Pages
610-617
Date Issued
2007
Date
2007
Author(s)
CHUANG, KAI-JEN
CHAN, CHANG-CHUAN
Abstract
Objective: It is still unknown whether specific components in fine particles are associated with heart rate variability (HRV) reduction. Methods: We recruited 46 patients with or at risk for cardiovascular diseases to measure 24-hour HRV by ambulatory electrocardiographic monitoring. Fixed-site air-monitoring stations were used to represent participants' exposures to particles with aerodynamic diameters less than 10 [mu]m (PM 10) and 2.5 [mu]m (PM2.5), and particulate components of sulfate, nitrate, organic carbon (OC) and elemental carbon, and gaseous pollutants. Results: We found that HRV reduction was associated with sulfate, OC, and PM2. 5 but not with the other five pollutants in single-pollutant models. Sulfate was found to remain in significant association with HRV reduction adjusting for OC and PM2.5 in three-pollutant models. Conclusions: Exposures to sulfate and OC in PM2.5 were associated with HRV reduction in patients with or at risk for cardiovascular diseases.
Subjects
Sulfate
Organic Carbon
Heart Rate Variability
SDGs
Type
journal article