The Relationship of Penile Rigidity and Intracavernous Vascular Resistance in Potent Men during Intracavernous Pharmacological Testing
Resource
JOURNAL OF UROLOGY v.166 n.5 pp.1762-1765
Journal
JOURNAL OF UROLOGY
Journal Volume
v.166
Journal Issue
n.5
Pages
1762-1765
Date Issued
2001
Date
2001
Author(s)
CHEN, JYH-HORNG
LIU, SHIH-PING
HSIEH, JU-TON
Abstract
Purpose: We studied the relationship of penile rigidity and intracavernous vascular resistance in potent men during intracavernous pharmacological testing. Materials and Methods: Enrolled in our study were 19 potent men undergoing intracavernous pharmacological testing for various reasons. Hemodynamic changes in response to the intracavernous injection of 20 mug. prostaglandin E1 were assessed by color Doppler sonography with simultaneous RigiScan (Dacomed Corp ., Minneapolis, Minnesota) monitoring of penile rigidity. The relationship of penile rigidity and intracavernous vascular resistance was determined by correlating hemodynamic data with recorded penile rigidity values. Results : Maximal mean rigidity plus or minus standard deviation of the penile tip and base after intracavernous injection of prostaglandin E1 was 76.8% +/- 8.5% and 97.3% + /- 4.7%, respectively. Penile tip and base rigidity correlated positively with the resistive index (r = 0.69 and 0.75, p <0. 0001) and negatively with end diastolic velocity (r = -0.62 and -0.70, respectively, p <0.0001). The formula, rigidity = -128 + 195 X resistive index, was derived to describe the linear regression of penile base rigidity and the resistive index. The formula, rigidity = 59.8 3.3 X end diastolic velocity, was derived to describe the linear regression of penile base rigidity and end diastolic velocity. Conclusions: Penile rigidity correlated strongly with intracavernous vascular resistance in potent men during intracavernous pharmacological testing. The resistive index and end diastolic velocity of the cavernous arteries may each be used to estimate penile rigidity quantitatively.
Subjects
penis
vascular resistance
penile erection
alprostadel
STRUCTURAL-DYNAMIC RELATIONSHIPS
ENGINEERING ANALYSIS