Decision Modelling of Economic Evaluation of Intervention Programme of Breast Cancer
Resource
JOURNAL OF EVALUATION IN CLINICAL PRACTICE v.16 n.6 pp.1282-1288
Journal
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
Journal Volume
v.16
Journal Issue
n.6
Pages
1282-1288
Date Issued
2011
Date
2011
Author(s)
CHANG, JUNG-CHEN
Abstract
Objectives Economic appraisal of an intervention is a complex and multivariable problem, with probabilistic issues related not only to clinical outcomes but also to costs and willingness to pay. Methods We provide a comprehensive framework for economic appraisal of a health intervention to prevent beast cancer mortality, involving probabilistic model of costs as well as of aspects of the disease process. The economic appraisal can give a range of probabilities of cost-effectiveness depending on willingness or ability to pay. Results We apply the method to the example of polychemotherapy for early breast cancer. Results indicate a 30% probability of cost-effectiveness for a willingness to pay of $60 000 per quality-adjusted life-year and around 50% for a threshold of $100 000. Conclusion The comprehensive economic appraisal model is a powerful tool for decision making over a range of economic environments.
Subjects
breast cancer
cost-benefit analysis
cost-effectiveness analysis
cost-utility analysis
decision model
Markov model
probabilistic approach
SDGs