Trajectories of serum hepatitis B surface antigen kinetics in patients with chronic hepatitis B receiving long-term nucleos(t)ide analogue therapy
Journal
Liver international
Journal Volume
38
Journal Issue
4
Pages
627
Date Issued
2018-04
Author(s)
Hsu, Wei-Fan
Chen, Chuen-Fei
Lai, Hsueh-Chou
Su, Wen-Pang
Lin, Chia-Hsin
Chuang, Po-Heng
Chen, Sheng-Hung
Chen, Ching-Hsiang
Wang, Hung-Wei
Peng, Cheng-Yuan
Abstract
The kinetics of serum hepatitis B surface antigen (HBsAg) levels during long-term nucleos(t)ide analogue (NA) therapy in chronic hepatitis B (CHB) patients remains unclear. We investigated the patterns of serum HBsAg kinetics and their association with therapeutic outcomes in genotype B- or C-infected CHB patients receiving long-term NA therapy.
Subjects
HBsAg loss; chronic hepatitis B; group-based trajectory models; hepatitis B surface antigen; nucleos(t)ide analogue
SDGs
Publisher
WILEY
Type
journal article