INACTIVATION OF VIRUS-CONTAINING AEROSOLS BY ULTRAVIOLET GERMICIDAL IRRADIATION
Resource
AEROSOL SCIENCE AND TECHNOLOGY v.39 n.12 pp.1136-1142
Journal
AEROSOL SCIENCE AND TECHNOLOGY
Journal Volume
v.39
Journal Issue
n.12
Pages
1136-1142
Date Issued
2005
Date
2005
Author(s)
TSENG, CHUN-CHIEH
LI, CHIH-SHAN
Abstract
The increasing incidence of infectious diseases has prompted the application of Ultraviolet Germicidal Irradiation (UVGI ) for the inactivation of viruses. This study evaluates UVGI effectiveness for airborne viruses in a laboratory test chamber by determining the effect of UV dosage, different nucleic acid type of virus (single- stranded RNA, ssRNA; single-stranded DNA, ssDNA; double- stranded RNA, dsRNA; and double-stranded DNA, dsDNA), and relative humidity on virus survival fraction after UVGI exposure. For airborne viruses, the UVGI dose for 90% inactivation was 339–423 μW sec/cm 2 for ssRNA, 444–494 μW sec/cm 2 for ssDNA, 662–863 μW sec/cm 2 for dsRNA, and 910–1196 μW sec/cm 2 for dsDNA. For all four tested, the UVGI dose for 99% inactivation was 2 times higher than that for 90% inactivation. Airborne viruses with single-stranded nucleic acid (ssRNA and ssDNA) were more susceptible to UV inactivation than were those with double-stranded ones ( dsRNA and dsDNA). For all tested viruses at the same inactivation, the UVGI dose at 85% RH was higher than that at 55% RH, possibly because water sorption onto a virus surface provides protection against UV -induced DNA or RNA damage at higher RH. In summary, UVGI was an effective method for inactivation of airborne virus.
SDGs
Type
journal article