Daptomycin area under the curve to minimum inhibitory concentration ratio by broth microdilution for predicting the outcome of vancomycin-resistant Enterococcus bloodstream infection
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Journal Volume
155
Date Issued
2022-11
Author(s)
HSIN-YI LIN
Yang, Jia-Ling
Lin, Chi-Ying
Huang, Sung-Hsi
Abstract
Different methods are used to determine the minimum inhibitory concentration (MIC) for daptomycin. The threshold is unknown for the free drug area under the concentration-time curve to MIC ratio (fAUC/MIC) of daptomycin using broth microdilution (BMD) to predict outcome of vancomycin-resistant enterococcus (VRE) bacteremia. The MIC testing method which is best for predicting the outcome remains unclear.
Subjects
Daptomycin; Minimum inhibitory concentration; Mortality; Pharmacodynamic; Vancomycin-resistant enterococci
SDGs
Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Type
journal article