Study of Canine Atopic Dermatitis
Date Issued
2009
Date
2009
Author(s)
Sung, Tzu-Yang
Abstract
Atopic dermatitis is a common canine allergic skin disease with characteristics of genetic predisposition, early onset of clinical signs, and antigen-specific IgE antibodies. Definitive diagnosis of canine atopic dermatitis and identification of the offending allergens were based on the intradermal skin test. Both in humans and dogs, superficial mycosis was considered an aggravating factor in the control of atopic dermatitis. This thesis includes two studies, to evaluate the prevalence of positive intradermal skin test reactions in dogs with atopic dermatitis and the prevalence of cutaneous mycosis in atopic dogs. Results of the first study showed that house dust (72%) was the most common allergen in the tested dogs, followed by Dermatophagoides farinae (70%), D. pteronyssinus (70%), house mite mix (68%) and an insect mix (33%). Dogs with positive reactions to house dust also had reactions that positively correlated with reactions to mite mix (P < 0.0001) and to D. pteronyssinus (P < 0.05). Fifty-one dogs (72%) exhibited signs of atopic dermatitis before three years of age and this condition was significantly more common in male than female dogs (P=0.006). Results of the second study revealed that the overall prevalence of dermatophytosis in atopic dogs was 56% (52/93) and among the isolates identified, Microsporum canis was the most common dermatophyte (7%, 6/93). Malassezia pachydermatis was isolated in 10% (9/93) of the dogs and the saprophyte carriage rate was 12% (11/93). Dogs less than one year of age were significantly susceptible to cutaneous mycoses (P<0.001) and the infection was not affected by breed or gender.
Subjects
ATOPIC DERMATITIS
DERMATITIS
HOUSE DUST
MITE
MICROSPORUM CANIS
SDGs
Type
thesis
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