Gallium maltolate shows synergism with cisplatin and activates nucleolar stress and ferroptosis in human breast carcinoma cells
Journal
Cellular oncology (Dordrecht)
Date Issued
2023-04-17
Author(s)
Abstract
Breast cancer is the most common cancer in women. Triple-negative breast cancer (TNBC) is an aggressive disease with poor outcomes. TNBC lacks effective targeted treatments, and the development of drug resistance limits the effectiveness of chemotherapy. It is crucial to identify new drugs that can enhance the efficacy of traditional chemotherapy to reduce drug resistance and side effects.
Subjects
Cisplatin; Ferroptosis; Gallium maltolate; Nucleolar stress; Triple-negative breast cancer
Type
journal article