Charlson comorbidity index predicts outcomes of elderly after allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
120
Journal Issue
12
Pages
2144
Date Issued
2021-12
Author(s)
Chien, Sheng-Hsuan
Li, Chi-Cheng
Chang, Ping-Ying
Yu, Ming-Sun
Huang, Cih-En
Tan, Tran-Der
Lin, Cheng-Hsien
Yeh, Su-Peng
Li, Sin-Syue
Wang, Po-Nan
Liu, Yi-Chang
Gau, Jyh-Pyng
Abstract
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the curative therapy for acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS), but advanced age with multiple comorbidities limits the eligibility for allo-HSCT. We conducted a retrospective study to investigate the comorbidities assessments and prognostic factors that predict outcomes for these patients.
Subjects
Acute leukemia; Allogeneic hematopoietic stem cell transplantation; Charlson comorbidity index; Elderly adult; Myelodysplastic syndrome
Type
journal article