The Influence of Helicobacter Pylori Infection on the Development of Gastric Ulcer in Symptomatic Patients after Bariatric Surgery
Resource
OBESITY SURGERY v.16 n.6 pp.735-739
Journal
OBESITY SURGERY
Journal Volume
v.16
Journal Issue
n.6
Pages
735-739
Date Issued
2006
Date
2006
Author(s)
YANG, CHANG-HSUEH
LEE, WEI-JEI
WANG, HSIH-HSI
HUANG, SHIH-PEI
LIN, JAW-TOWN
WU, MING-SHIANG
Abstract
Background: There are few data relating to the role of H. pylori infection and surgical procedures on the occurrence of gastric ulcer following bariatric surgery. Methods: Subjects with upper gastrointestinal symptoms after bariatric surgery and receiving gastroscopic examinations were prospectively enrolled. All clinical data including age , sex, BMI before surgery, and surgical method were recorded . IgG antibodies against H. pylori were measured in preoperative serum by enzyme-linked immunosorbent assay ( ELISA). Results: A cohort of 636 patients undergoing laparoscopic vertical banded gastroplasty (LVBG) or Roux-en- Y gastric bypass (LRYGBP) was recruited. The seropositivity of H. pylori in symptomatic and asymptomatic patients after surgery was 39%.(32/82) and 39 .7% (220/554) respectively. Endoscopic examinations revealed that 22 (26.8 %) of 82 symptomatic patients had a gastric ulcer. Comparison of demographic characteristics between patients with ulcer (n = 22) and patients without ulcer (n = 60) showed no difference in distribution of gender, age, BMI, and seroprevalence of H. pylori (27.3%, 6/22 vs 43.3%, 26/60, P= 0.212). Patients undergoing LRYGBP showed a higher rate of gastric ulcer (45.5%, 10/22) when compared to patients undergoing LVBG (20 %, 12/60; P = 0.027). Conclusion: Gastric ulcers in symptomatic patients following laparoscopic bariatric surgery are related to surgical procedures rather than exposure to A pylori infection.
Subjects
gastric ulcer
bariatric surgery
morbid obesity
Helicobacter pylori
gastroplasty
gastric bypass
SDGs
Type
journal article