Regulatory SNPs Alter the Gene Expression of Diabetic Retinopathy Associated Secretary Factors
Journal
International journal of medical sciences
Journal Volume
13
Journal Issue
9
Date Issued
2016
Author(s)
Chen, Chian-Feng
Liou, Shiow-Wen
Wu, Hsin-Han
Lin, Chin-Hui
Huang, Li-Shan
Tsai, Ching-Yao
Abstract
Diabetic retinopathy (DR) is a common microvascular complication in both type I and type II diabetes. Several previous reports indicated the serum centration of some secretary factors were highly associated with DR. Therefore, we hypothesis regulatory SNPs (rSNPs) genotype in secretary factors may alter these gene expression and lead to DR.
Subjects
DR; SNP; VEGFA.
Type
journal article