Impact of the COVID-19 Pandemic on Global TAVR Activity: The COVID-TAVI Study.
Journal
JACC. Cardiovascular interventions
Journal Volume
17
Journal Issue
3
ISSN
1876-7605
Date Issued
2024-02-12
Author(s)
Armario, Xavier
Carron, Jennifer
Simpkin, Andrew J
Elhadi, Mohamed
Kennedy, Ciara
Abdel-Wahab, Mohamed
Bleiziffer, Sabine
Lefèvre, Thierry
Wolf, Alexander
Pilgrim, Thomas
Villablanca, Pedro A
Blackman, Daniel J
Van Mieghem, Nicolas M
Hengstenberg, Christian
Swaans, Martin J
Prendergast, Bernard D
Patterson, Tiffany
Barbanti, Marco
Webb, John G
Behan, Miles
Resar, Jon
Chen, Mao
Hildick-Smith, David
Spence, Mark S
Zweiker, David
Bagur, Rodrigo
Teles, Rui
Ribichini, Flavio L
Jagielak, Dariusz
Park, Duk-Woo
Kornowski, Ran
Wykrzykowska, Joanna J
Bunc, Matjaz
Estévez-Loureiro, Rodrigo
Poon, Karl
Götberg, Matthias
Jeger, Raban V
Ince, Hüseyin
Packer, Erik J S
Angelillis, Marco
Nombela-Franco, Luis
Guo, Yingqiang
Savontaus, Mikko
Al-Moghairi, Abdulrahman M
Parasca, Catalina Andreea
Kliger, Chad
Roy, David
Molnár, Levente
Silva, Mariana
White, Jonathon
Yamamoto, Masanori
Carrilho-Ferreira, Pedro
Toggweiler, Stefan
Voudris, Vassileios
Ohno, Yohei
Rodrigues, Inês
Parma, Radosław
Ojeda, Soledad
Toutouzas, Kostas
Regueiro, Ander
Grygier, Marek
AlMerri, Khaled
Cruz-González, Ignacio
Fridrich, Viliam
de la Torre Hernández, José M
Noble, Stephane
Kala, Petr
Asmarats, Lluis
Kurt, Ibrahim Halil
Bosmans, Johan
Erglis, Martins
Casserly, Ivan
Iskandarani, Dounia
Bhindi, Ravinay
Kefer, Joelle
Yin, Wei-Hsian
Rosseel, Liesbeth
Kim, Hyo-Soo
O'Connor, Stephen
Hellig, Farrel
Sztejfman, Matias
Mendiz, Oscar
Pineda, Andres M
Seth, Ashok
Pllaha, Elton
de Brito, Fabio S
Bajoras, Vilhelmas
Balghith, Mohammed A
Lee, Michael
Eid-Lidt, Guering
Vandeloo, Bert
Vaz, Vinicius Daher
Alasnag, Mirvat
Ussia, Gian Paolo
Tay, Edgar
Mayol, Jorge
Gunasekaran, Sengottuvelu
Sardella, Gennaro
Buddhari, Wacin
Dager, Antonio
Tzikas, Apostolos
Gudmundsdottir, Ingibjörg J
Edris, Ahmad
Gutiérrez Jaikel, Luis Abel
Arias, Eduardo A
Al-Hijji, Mohammed
Ertürk, Mehmet
Conde-Vela, César
Boljević, Darko
Ferrero Guadagnoli, Adolfo
Hermlin, Toomas
ElGuindy, Ahmed M
Lima-Filho, Moysés de Oliveira
de Moura Santos, Luciano
Perez, Luis
Maluenda, Gabriel
Akyüz, Ali Rıza
Alhaddad, Imad A
Amin, Haitham
So, Chak-Yu
Al Nooryani, Arif A
Vaca, Carlos
Albistur, Juan
Nguyen, Quang Ngoc
Arzamendi, Dabit
Grube, Eberhard
Modine, Thomas
Tchétché, Didier
Hayashida, Kentaro
Latib, Azeem
Makkar, Raj R
Piazza, Nicolo
Søndergaard, Lars
McEvoy, John William
Mylotte, Darren
Abstract
The COVID-19 pandemic adversely affected health care systems. Patients in need of transcatheter aortic valve replacement (TAVR) are especially susceptible to treatment delays.
This study sought to evaluate the impact of the COVID-19 pandemic on global TAVR activity.
This international registry reported monthly TAVR case volume in participating institutions prior to and during the COVID-19 pandemic (January 2018 to December 2021). Hospital-level information on public vs private, urban vs rural, and TAVR volume was collected, as was country-level information on socioeconomic status, COVID-19 incidence, and governmental public health responses.
We included 130 centers from 61 countries, including 65,980 TAVR procedures. The first and second pandemic waves were associated with a significant reduction of 15% (P < 0.001) and 7% (P < 0.001) in monthly TAVR case volume, respectively, compared with the prepandemic period. The third pandemic wave was not associated with reduced TAVR activity. A greater reduction in TAVR activity was observed in Africa (-52%; P = 0.001), Central-South America (-33%; P < 0.001), and Asia (-29%; P < 0.001). Private hospitals (P = 0.005), urban areas (P = 0.011), low-volume centers (P = 0.002), countries with lower development (P < 0.001) and economic status (P < 0.001), higher COVID-19 incidence (P < 0.001), and more stringent public health restrictions (P < 0.001) experienced a greater reduction in TAVR activity.
TAVR procedural volume declined substantially during the first and second waves of the COVID-19 pandemic, especially in Africa, Central-South America, and Asia. National socioeconomic status, COVID-19 incidence, and public health responses were associated with treatment delays. This information should inform public health policy in case of future global health crises.
Subjects
aortic valve stenosis
coronavirus disease 2019
transcatheter aortic valve replacement
valvular heart disease
SDGs
Type
journal article