Mechanistic Study of Apatite Formation on Bioactive Glass Surface Using Solid-State NMR Spectroscopy
Date Issued
2005
Date
2005
Author(s)
Lin, Hsiang-Kai
DOI
zh-TW
Abstract
The molecular mechanism of apatite formation on bioactive glass surface is studied using the techniques of XRD, EDX, SEM, FT-IR, and solid-state NMR. Using the sol-gel method a bioactive glass system containing glass beads of 2 to 3 microns in size is prepared with the composition containing 30 % CaO – 70 % SiO2. Our experimental data support the apatite formation mechanism proposed by Hench concerning the precipitation and crystallization of calcium phosphate. The phosphate ions initially deposited on the glass surface are largely amorphous and have substantial amount of water molecules in the surrounding. As the soaking time in simulated body fluid increases, some of the water molecules diffuse out of the phosphate lattice, leading to the formation of a crystalline phase. Our data show that the structure of the crystalline phase is different from type B carbonate apatite but similar to hydroxyapatite.
Subjects
羥基磷灰石
生物活性玻璃
固態核磁共振
Apatite
Bioactive Glass
Solid-State NMR
Type
thesis
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