Short-term effects of air pollution on pulse pressure among nonsmoking adults
Journal
Epidemiology
Journal Volume
23
Journal Issue
2
Pages
341-348
Date Issued
2012
Author(s)
Abstract
Background: Previous studies on the effects of acute air pollution have focused primarily on blood pressure (BP). Methods: Our study enrolled 9238 nonsmoking adults over 30 years of age from 6 townships in Taiwan: 1 seaport, 1 urban, 1 industrial, and 3 rural. Using generalized additive models, we evaluated the associations between brachial BP and short-term exposure to 5 air pollutants: particulate matter with diameter <10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3). Results: After adjusting for individual and meteorologic factors, the systolic BP was decreased by all 5 pollutants, whereas the diastolic BP was increased by SO2, NO 2, and O3. The pulse pressure was consistently decreased by all 5 pollutants, with changes of -1.5 (95% confidence interval = -2.0 to -1.1), -0.6 (-0.9 to -0.4), -2.4 (-3.0 to -1.8), -1.2 (-1.6 to -0.9), and -1.4 (-1.8 to -0.9) mm Hg for interquartile range increases in 3-day lagged PM 10, SO2, NO2, carbon monoxide, and O 3, respectively. PM10 exposure was more strongly associated with reduction of pulse pressure among men, persons >60 years of age, those with hypertension, and those living in the industrial township. Conclusions: Short-term exposure to air pollution reduces pulse pressure. PM10 in industrial emissions may contribute to pulse pressure changes. Age, sex, and hypertensive status may modify the effects of PM 10 on pulse pressure. Copyright © 2012 by Lippincott Williams & Wilkins.
SDGs
Other Subjects
carbon monoxide; nitrogen dioxide; ozone; sulfur dioxide; adult; air pollutant; air pollution; article; blood pressure measurement; brachial artery; diastolic blood pressure; environmental exposure; female; human; hypertension; major clinical study; male; particulate matter; priority journal; pulse pressure; questionnaire; rural area; systolic blood pressure; Taiwan; urban area; Air Pollutants; Air Pollution; Blood Pressure; Carbon Monoxide; Environmental Exposure; Female; Humans; Male; Middle Aged; Nitrogen Dioxide; Ozone; Particulate Matter; Sulfur Dioxide; Taiwan; Time Factors; Weather
Type
journal article