奈米微粒與健康風險研究─子計畫四：奈米生物性氣膠採樣與分析探討(III)(2/2)

The increasing incidence of infectious diseases has prompted the application of
Ultraviolet Germicidal Irradiation (UVGI) for
the inactivation of viruses. This study
evaluates UVGI effectiveness for both
airborne and surface viruses in a laboratory
test chamber by determining the effect of UV
dosage, different nucleic acid type of virus,
and relative humidity on virus survival
fraction after UVGI exposure. For airborne
viruses, the UVGI dose for 90% inactivation
was 339-423 μ W sec/cm2 for ssRNA, and
662-863 μ W sec/cm2 for dsRNA. For all
tested, the UVGI dose for 99% inactivation
was 2 times higher than that for 90%
inactivation, and the ratio of surface to
airborne UVGI dose ranged from 3.9 to 7.6.
Airborne and surface viruses with
single-stranded nucleic acid were more
susceptible to UV inactivation than were
those with double-stranded ones. For all
tested viruses at the same inactivation, the
UVGI dose at 85% RH was higher than that
at 55% RH, possibly because water sorption
onto a virus surface provides protection
against UV-induced RNA damage at higher
RH. In summary, UVGI was an effective
method for virus inactivation.