MAP7D3, a novel prognostic marker for triple-negative breast cancer, drives cell invasiveness and cancer-initiating cell properties to promote metastatic progression
Journal
Biology direct
Journal Volume
18
Journal Issue
1
Date Issued
2023-08-07
Author(s)
Abstract
Patients with triple-negative breast cancer (TNBC) tend to develop visceral metastasis within five years, making them the most challenging BC patients to treat. The MAP7 protein family is a group of microtubule-binding proteins with a well-known role in microtubule-related cell migration, but its role in metastasis-related properties of TNBC remains unclear.
Subjects
Breast cancer-initiating cells.; MAP7D3; Metastasis; Triple-negative breast cancer
Type
journal article