Sarcopenia is Related to Increased Risk for Low Bone Mineral Density
Journal
Journal of Clinical Densitometry
Journal Volume
16
Journal Issue
1
Pages
98-103
Date Issued
2013
Author(s)
Abstract
Lean body mass is positively correlated with bone mineral density (BMD). The association between sarcopenia and BMD is less studied. The aim of the study is to investigate the association between sarcopenia and abnormal BMD. A total of 600 community residents aged 40-85yr (mean=63.63±10.12) from Taipei, Taiwan were included. Abnormal and normal BMD groups were categorized by T-score of femoral neck and lumbar spine (L2-L4) measured by dual-energy X-ray absorptiometry. Skeletal muscle mass (SM) index (SMI) was obtained from SM divided by height squared using bioelectrical impedance analysis (BIA) method. Sarcopenia was defined as SMI less than 8.87kg/m2 in men and 6.42kg/m2 in women according to previous Taiwanese sarcopenia study. The association between BMD groups and sarcopenia was examined using binary logistic regression analyses after controlling potential confounders. Subjects with sarcopenia were at higher risk for low BMD (odds ratio (OR) = 1.59, 95% confidence interval (CI)=1.06-2.39 for femoral neck BMD and OR=1.72, 95% CI=1.09-2.72 for lumbar BMD) compared with the nonsarcopenia group. Even in different gender groups with age categorized, sarcopenia was still an important independent factor in female group. The least square (LS) means of BMD of femoral neck and lumbar spine were significantly lower in sarcopenia group. The risk of low BMD increased significantly with sarcopenia. ? 2013 The International Society for Clinical Densitometry.
SDGs
Other Subjects
adult; aged; article; bioelectrical impedance analysis; bone density; community; disease association; dual energy X ray absorptiometry; female; femur neck; human; impedance; lumbar spine; major clinical study; male; muscle atrophy; musculoskeletal system parameters; priority journal; risk assessment; skeletal muscle mass index; Taiwan; Aged; Aged, 80 and over; Body Composition; Bone Density; Electric Impedance; Female; Femur Neck; Humans; Logistic Models; Lumbar Vertebrae; Male; Middle Aged; Sarcopenia
Type
journal article