Ocular manifestations of patients receiving heart transplants: A single-center experience of 311 consecutive cases
Journal
Transplantation Proceedings
Journal Volume
46
Journal Issue
3
Pages
937-940
Date Issued
2014
Abstract
Purpose: The purpose of this study was to investigate ocular manifestations of patients undergoing heart transplantations.
Method: We retrospectively reviewed the clinical data of 311 patients who underwent orthotropic heart transplantations from January 1989 to December 2007, including the demographic data, general conditions, medications, as well as the basic ophthalmic examinations, ophthalmic diagnosis, and management.
Results: Of the 311 heart transplant recipients, common diagnoses included cataract (96 cases; 30.87%), dry eye syndrome (24 cases; 7.72%), allergic conjunctivitis (78 cases; 25.08%), and glaucoma (19 cases; 6.11%). The patients after heart transplantation had much lower incidences of severe opportunistic infections than patients undergoing the same procedure one decade ago. However, autoimmune-related endocrinopathy such as diabetes and Graves' disease became more prevalent. Diabetes-related complications were unexpectedly frequent, including nonproliferative diabetic retinopathy (6 cases; 1.93%), proliferative diabetic retinopathy (6 cases; 1.93%), retinal vein occlusion (6 cases; 1.93%), and neovascular glaucoma (4 cases; 1.29%). The occurrence of cataract formation and steroid glaucoma was often due to post-transplantation steroid use.
Conclusion: Ophthalmologists and cardiac surgeons should collaborate and perform regular ophthalmic examinations, especially for those who have new-onset diabetes and difficulty tapering off steroids.
SDGs
Other Subjects
amiodarone; immunosuppressive agent; steroid; adult; allergic conjunctivitis; branch retinal vein occlusion; cataract; central retina vein occlusion; central serous retinopathy; clinical feature; conference paper; demography; diabetes mellitus; diabetic retinopathy; dry eye; epiretinal membrane; eye disease; eye examination; female; glaucoma; Graves disease; heart graft; heart transplantation; herpes zoster ophthalmicus; human; incidence; keratoconjunctivitis; keratopathy; lens subluxation; major clinical study; male; myopic maculopathy; neovascular glaucoma; opportunistic infection; priority journal; retina detachment; retina macula age related degeneration; retina maculopathy; retina vein occlusion; retrospective study; classification; Eye Diseases; heart transplantation; middle aged; Adult; Eye Diseases; Female; Heart Transplantation; Humans; Male; Middle Aged; Retrospective Studies
Publisher
Elsevier USA
Type
conference paper