Rapid intraoperative margin assessment by using multi-modal third-harmonic generation and three-photon fluorescence microscopy
Journal
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Journal Volume
11073
Date Issued
2019
Author(s)
Abstract
Slide-free imaging of hematoxylin-eosin-stained whole mount tissues is demonstrated using multi-modal third harmonic generation and three photon fluorescence microscopy. As a result, the demonstrated microscopy shows promise for rapid margin assessment during surgery without compromising the contrast and features of conventional H&E histology.
Publisher
SPIE
Type
conference paper