The prevalence of gastroesophageal reflux in anesthetized dogs
Date Issued
2008
Date
2008
Author(s)
Lin, Yi-Hsuan
Abstract
Objective To investigate the incidence and risk factors of gastroesophageal reflux in anesthetized dogs undergoing various surgical procedures. nimals A total of 100 dogs, 6.9 ± 4.5 years old, weighing 10.8 ± 9.6 kgethods The study group was dogs presenting to the National Taiwan University Veterinary Hospital for non-gastrointestinal procedures and surgeries requiring general anesthesia. Dogs with chronic gastrointestinal diseases or being persistently treated with drugs known to affect gastric motility/physiology and the tone of gastroesophageal sphincter were excluded.he premedication protocol was designed by anesthetists according to the physical status and the nature surgical procedure. All dogs were induced with propofol to achieve endotracheal intubation. Anesthesia was maintained with isoflurane in oxygen. Esophageal pH probe was placed during anesthesia. The gastroesophageal reflux was defined as the esophageal pH value under 4.0 or increasing above 7.5.esults Thirty-five dogs experienced gastroesophageal reflux during anesthesia, with a total of 44 episodes. The dosage of induction propofol and the duration of anesthesia had positive correlation with the risk of gastroesophageal reflux. The incidence of alkaline reflux was much higher than previously reported. In 3 episodes of alkaline reflux, only 1 showed bilirubin positive.onclusions and Clinical relevance The risk of gastroesophageal reflux associating with induced propofol is dose-dependent. And all dogs have risk of reflux regardless of the length of anesthesia. Although measuring esophageal pH is the gold standard in diagnosing gastroesophageal reflux, esophageal secretion may contribute to false positive interpretation of alkaline reflux.
Subjects
dog
gastroesophageal reflux
alkaline reflux
Type
thesis
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