In vivo effect of platelet gel on human tendon and ligament healing: A narrative review
Journal
Regenerative Therapy
Journal Volume
29
Start Page
390
End Page
396
ISSN
2352-3204
Date Issued
2025-06
Author(s)
Abstract
Tendon and ligament injuries remain a significant challenge for clinicians, despite considerable efforts to develop effective treatment methods. This study reviewed in vivo human studies investigating the use of platelet gel, a blood-derived biomaterial that enhances tissue healing, for treating tendon and ligament injuries. Only eight relevant articles were identified, highlighting the limited number of available studies on this topic. Of these eight articles, three reported significant positive treatment effects, two found no significant benefit, and three observed varying degrees of improvement, although not always statistically significant. Overall, six of the eight studies indicated positive effects of platelet gel based on clinical and radiographic outcomes, suggesting its potential as a promising treatment. Further clinical studies are required to confirm its efficacy and establish its role in tendon and ligament healing.
Subjects
Biomaterial
Platelet-rich plasma
Regenerative medicine
Tear
Tendinopathy
SDGs
Publisher
Elsevier BV
Type
review