Incidence of Venous Thromboembolism in Asian Populations: A Systematic Review
Journal
Thrombosis and Haemostasis
Journal Volume
117
Journal Issue
12
Pages
2243-2260
Date Issued
2017
Author(s)
Abstract
Introduction Despite a marked recent increase in the number of publications describing the incidence of venous thromboembolism (VTE) in Asia, and especially in mainland China, Hong Kong, Taiwan, Korea, Japan and Singapore, there remains a lack of consensus on the true risks, and trends over time, to inform appropriate clinical practice. The purpose of this systematic review was therefore to examine evidence about the incidence of symptomatic VTE in Asia. Methods Databases were searched for studies from Asia, published between January 1995 and February 2016, on the incidence of symptomatic VTE, deep vein thrombosis (DVT) or pulmonary embolism. Review of eligible studies was conducted independently by two reviewers. Data were extracted on incidence, predispositions and recurrence of VTE. Results One thousand nighty-five studies were identified, of which 73 were eligible for full text review and data extraction. Three population-wide estimates of VTE rates identified from Korea, Taiwan and Hong Kong reported annual incidences of 13.8, 15.9 and 19.9 per 100,000, respectively. Nine studies of Asian hospital registries or databases reported VTE rates ranging from 11 to 88 cases per 10,000 admissions. Population-based estimates of post-surgical DVT rates ranged from 0.15 to 1.35%. Age was a significant risk factor for VTE in all population groups. Conclusion Population-wide incidence estimates in Asia were approximately 15 to 20% of the levels recorded in western countries but have increased over time. It is anticipated this synthesis of evidence on the incidence of VTE and its predisposing factors will increase awareness about VTE in Asian populations. ? 2017 Schattauer.
Subjects
Asian population; deep vein thrombosis; epidemiology; pulmonary embolism; venous thromboembolism
SDGs
Other Subjects
arthroplasty; Asian; atrial fibrillation; brain hemorrhage; carbon monoxide intoxication; disease predisposition; gender; gynecologic surgery; hormone substitution; hospital discharge; human; ICD-10; ICD-9; incidence; liver cirrhosis; malignant neoplasm; mortality rate; non insulin dependent diabetes mellitus; pregnancy; prevalence; priority journal; recurrence risk; Review; senescence; sleep disorder; spinal cord injury; systematic review; venous thromboembolism; animal; Asia; female; incidence; male; population group; risk; venous thromboembolism; Animals; Asia; Female; Humans; Incidence; Male; Population Groups; Risk; Venous Thromboembolism
Publisher
Georg Thieme Verlag
Type
review