Cellular models for the evaluation of the antiobesity effect of selected phytochemicals from food and herbs
Journal
Journal of Food and Drug Analysis
Journal Volume
25
Journal Issue
1
Pages
100-110
Date Issued
2017
Author(s)
Abstract
Dietary phytochemicals from food and herbs have been studied for their health benefits for a long time. The incidence of obesity has seen an incredible increase worldwide. Although dieting, along with increased physical activity, seems an easy method in theory to manage obesity, it is hard to apply in real life. Obesity treatment drugs and surgery are not successful or targeted for everyone and can have significant side effects. This low rate of success is the major reason that the overweight as well as the pharmaceutical industry seek alternative methods, including phytochemicals. Therefore, more and more research has focused on the role of phytochemicals to alleviate lipid accumulation or enhance energy expenditure in adipocytes. This review discusses selected phytochemicals from food and herbs and their effects on adipogenesis, lipogenesis, lipolysis, oxidation of fatty acids, and browning in 3T3-L1 preadipocytes. ? 2016
Subjects
3T3-L1 cells; adipogenesis; lipogenesis; lipolysis; phytochemicals
SDGs
Other Subjects
antiobesity agent; hormone; plant medicinal product; sterol regulatory element binding protein 1c; uncoupling protein; plant extract; plant medicinal product; adipogenesis; animal cell; brown adipose tissue; cell differentiation; cell proliferation; dietary intake; fatty acid oxidation; food; herb; hormone blood level; in vitro study; lipid metabolism; lipogenesis; lipolysis; mouse; nonhuman; obesity; plant browning; plant cell; proadipocyte; protein expression; rat; Review; thermogenesis; white adipose tissue; adipogenesis; animal; human; medicinal plant; obesity; Adipogenesis; Animals; Food; Humans; Lipid Metabolism; Obesity; Phytochemicals; Plant Extracts; Plants, Medicinal
Type
journal article
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