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  4. Pulsatile flow past a cylinder: An experimental model of flow in an artificial lung
 
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Pulsatile flow past a cylinder: An experimental model of flow in an artificial lung

Journal
ASAIO Journal
Journal Volume
52
Journal Issue
6
Pages
614-623
Date Issued
2006
Author(s)
YU-CHUN LIN  
Brant D.O.
Bartlett R.H.
Hirschl R.B.
Bull J.L.
DOI
10.1097/01.mat.0000235281.49204.24
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-33751248501&doi=10.1097%2f01.mat.0000235281.49204.24&partnerID=40&md5=3c654549e3c7b9c8f1d94f2c5e829b5c
https://scholars.lib.ntu.edu.tw/handle/123456789/558317
Abstract
The focus of this study is an experimental apparatus that serves as a model for studying blood flow in a total artificial lung (TAL), a prototype device intended to serve as a bridge to lung transplantation or that supports pulmonary function during the treatment of severe respiratory failure. The TAL consists of hollow cylindrical fibers that oxygen-rich air flows through and oxygen-poor blood flows around. Because gas diffusivity in the TAL is very small, a convection mechanism dominates the gas transport, which is why we focus on the velocity around the fibers (modeled as a 0.05-cm-in-diameter and 5-cm-long cylinder). We designed a low-speed water tunnel to study the flow mechanism around the cylinder, across which the flow is generated by a linear actuator that allows different flow patterns to mimic the flow in a TAL. We tested the flow in the test section by numerical simulation and by the particle image velocimetry method to study the flow profile. The results show a uniform flow near the centerline of the water tunnel where the cylinder is placed. This decreases the effects of free-stream turbulence in the shear layers and reduces the uncertainty in determining the flow patterns around the cylinder. Knowledge gained from the flow around one cylinder (fiber) is beneficial for understanding vortex formation around multiple cylinders. We present a summary of vortex formation behind a cylinder for Reynolds numbers (Re) of 1, 3, and 5 and Stokes numbers (Ns) of 0.18 to 0.37; results show that higher Re and Ns favor vortex formation. These findings regarding the parameter range for vortex formation may provide principles for designing artificial lungs to enhance convective mixing. We anticipate that the pulsatile flow circuit presented here can be used to mimic the flow not only in TALs but in other physiological systems.
SDGs

[SDGs]SDG6

Type
journal article

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