An affinity sensor improved by ewod actuator-based microfluidic chip
Journal
Biomedical Engineering: Applications, Basis and Communications
Journal Volume
21
Journal Issue
6
Pages
461-465
Date Issued
2009
Author(s)
Abstract
We propose an improved immunoassay method with EWOD-based microfluidic biochip. Electro-wetting on dielectric (EWOD) is based on contact angle-changed phenomenon of droplet on the channel surface. The reactant-containing droplet can be moved from reservoir to a modified electrode area, which a stir function can be provided by controlling AC electro-osmosis flow (ACEOF). The immunochemistry reaction takes place on our modified area via electro-wetting actuation, and the signal from fluorescent or electrochemical impedance spectroscopy (EIS) was used to confirm the performance of designed element.
SDGs
Type
journal article